The Athina Palace Hotel is 12 km from the Thessaloniki town center, and is on the eastern side of the city. The Athina Palace Hotel is 2 km from the Thessaloniki Macedonia Airport. The airport can be reached by car.

There are 52 rooms at the Athina Palace Hotel, with modern amenities. The rooms have air conditioning, contemporary wood furniture, and all rooms have balconies. There is satellite television service, dial up Internet access, direct dial telephone service, and a mini bar.

The Athina Palace Hotel is a glass fronted leisure property with extensive wellness facilities. The Pelagos Club offers an indoor heated pool with massage jets, a massage service center, a sauna, a gym, and a games zone. Private fitness training and tennis coaching is also available on site. For business or social events, the hotel has a conference zone for up to 200 people with the latest technology installations. Dining options focus on traditional Greek cuisine served in the house restaurant. There is also a drinks lounge.